Wysłany: Sob 6:00, 28 Kwi 2007 Temat postu: Drugs is not for you
Orally administered [link widoczny dla zalogowanych] it is readily absorbed in man with peak plasma concentrations occurring 1 to 2 hours following administration. The half life range is 6 to 20 hours following single dose administration. With multiple doses, given 3 times daily, steady state is reached within 7 days. [link widoczny dla zalogowanych] and its metabolites are excreted primarily in the urine. Degradation occurs mainly by oxidation yielding the primary and secondary metabolites which are active and appear to have half-lives similar to alprazolam but are present at only low levels in the plasma. Alprazolam is 80% protein bound.